Generative and other forms of artificial intelligence are poised to revolutionize the business of human intelligence–espionage. The Digital Case Officer: Reimagining Espionage with AI informs U.S. Intelligence Community leaders, national security policymakers, Congress, and allied intelligence services about the impact that AI will likely have on the human intelligence mission within the next 1-3 years and it recommends specific actions that the U.S. IC can undertake to safely accelerate integration of this powerful new technology.